Mutational dynamics of SARS-CoV-2 in Austria
Andreas Bergthaler | Center for Molecular Medicine (CeMM)
(in collaboration with: Medical University of Vienna; Austian Agency for Health and Food Safety Ltd. (AGES) and other Austrian universities)
If you have any questions about the Call and the WWTF, please contact Michael Stampfer.
© Florian Tanzer
(in collaboration with: Medical University of Vienna; Austian Agency for Health and Food Safety Ltd. (AGES) and other Austrian universities)
(in collaboration with: Oliver H. Robak, Medical Univeristy of Vienna; Christoph Steininger,Medical Univeristy of Vienna; Christof Jungbauer, Austrian Red Cross; Volker Witt, St. Anna Children's Hospital; Hedda Wardemann, German Cancer Research Center (DKFZ); Florian Halbritter, Children's Cancer Research Insitute (CCRI); Matthias Farlik-Födinger, Medical Univeristy of Vienna)
(In collaboration with: Josef Penninger, University of British Columbia, IMBA & Apeiron; Johannes Stadlmann, IMBA & University of Natural Resources and Life Sciences)
(in collaboration with: Ali Mirazimi, Karolinska Institutet; Nuria Montserrat, Institute for Bioengineering of Catalonia (IBEC), Apeiron Biologics)
© Florian Tanzer
(in Kooperation mit Miriam Klausberger, University of Natural Resources and Life Sciences; Reingard Grabherr, University of Natural Resources and Life Sciences; Florian Grebien, Vetmeduni Vienna; Heinz Burgmann, Medical University of Vienna)
(in collaboration with: Max Perutz Labs, a Joint Venture of the Univeristy of Vienna and the Medical University of Vienna; University of Vienna; IMP; IMBA; GMI and other institutions in Vienna)
The COVID-19 pandemic poses an immediate enormous threat for healthcare systems and economies in Austria, Europe and the world. Many coping strategies are focused on “track-and-trace” identification of both infected and asymptomatic carriers of SARS-CoV-2. The Vienna COVID-19 Diagnostics Initiative was established with the aim of repurposing of standard laboratory infrastructure for enhanced testing capacity across institutional boundaries in Vienna. This entails the fully automated extraction of virus RNA, its detection by high-throughput qPCR, the production of in-house affordable reagents and the establishment of logistic/diagnostic interfaces with existing health care providers. We propose to generate an adaptable operating procedure that will aid other universities and research institutions to quickly contribute to the national testing capacity for COVID-19 or other emerging epidemics. We will generate and evaluate data on how such a pipeline is technically generated, how the pipeline is optimized, how protocols can be quickly disseminated and implemented and how the enhanced testing capacity will contribute to national efforts of virus suppression. This study is only possible in the context of the current crisis and the knowledge will be of immediate importance and broad relevance. The requested budget is for partly covering the implementation of the pipeline with a particular emphasis on evaluating pooling to further enhance throughput and does not cover the running costs for routine testing that we will offer as soon as the pipeline is fully functional.
Funding: € 50,000
Duration: 2 April 2020 - 1 November 2020
Contact and PI details: www.vcdi.net
(in collaboration with: Julius Brennecke, IMBA; Andrea Pauli, IMP; Ulrich Elling, IMBA; Stefan Ameres, IMBA; Alwin Köhler, University of Vienna/VCDI; Manuela Födinger (KFJ/KAV))
© Florian Tanzer
(in collaboration with: Wiener Krankenanstaltenverbund, Sigmund Freud Universität)
(in collaboration with: Complexity Science Hub; dwh GmbH; SpotOn Statistics GmbH, Statistik Austria)
(in collaboration with: Richard Crevenna, Medical University of Vienna; Maren Jeleff, Medical University of Vienna; Elena Jirovsky, Medical University of Vienna)
(in collaboration with: Medical University of Vienna)
(in collaboration with: David Garcia, Complexity Science Hub (CSH) and Medical University of Vienna)
(in collaboration with: Erika Mosor, Valentin Ritschl, Maisa Omara, Martin Posch, Franz König, Matthias Wielscher and Michael Hiesmayr, Medical University of Vienna; Susanne Perkhofer, FHG Innsbruck; Michael Schirmer, Medical University of Innsbruck; Angelika Rzepka, Bernhard Pfeifer, Peter Kastner and Anton Dunzendorfer, Austrian Institute of Technology; Florian Stigler and Martin Sprenger, Medical University of Graz; Siegfried Walch and Nils Mevenkamp, Management Center Innsbruck)
© Florian Tanzer
(in collaboration with: Sylvia Kritzinger, University of Vienna; Hajo Boomgaarden, University of Vienna; Barbara Prainsack, University of Vienna)
(in collaboration with: Institut for Socialanthropolog Austrian Academy of Sciences)
(in collaboration with: Arbeiterkammer Wien; Frauenabteilung)
© Florian Tanzer
(in collaboration with: Marko Lüftenegger, University of Vienna; Christiane Spiel, University of Vienna)
© Florian Tanzer
(in collaboration with Fraunhofer Austria; Bundesministerium für Digitalisierung und Wirtschaftsstandort; Bundeministerium für Landwirtschaft, Regionen und Tourismus; Universität Salzburg; Universität Klagenfurt)
(in collaboration with: Thomas Lindner, Jakob Müllner, Michael Wolfesberger (WU Vienna); Andreas König, Universität Passau; Oesterreichische Nationalbank (OeNB); Wirtschaftskammer Österreich (WKO))
(in cooperation with: Manfred Gronalt, Medical University of Vienna; Beate Pinior, University of Natural Resources and Life Sciences; Vetmeduni Vienna)